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Friday, November 22, 2024

Bayer’s pharma business in Asia Pacific drives growth in 2021; More innovative medicines to be launched

  • Pharmaceuticals division’s sales in the Asia/Pacific region grew 4.8%* to more than €5.8 billion in 2021
  • This marked the tenth consecutive year of growth for Bayer’s Pharmaceuticals Division in the region
  • Four upcoming major launches of innovative treatments Finerenone, Vericiguat, Larotrectinib and Darolutamide underscore Bayer’s commitment to reduce burden of cardiovascular diseases and cancer in the APAC region

SINGAPORE — Bayer announced that 2021 was another record year for its Pharmaceuticals Division in the Asia/Pacific region, with robust growth of 4.8%* delivering sales of more than €5.8 billion. Business in the region contributed to almost one-third of Bayer’s pharmaceuticals global sales.

Despite lingering COVID-19 challenges, sales of Bayer’s Pharmaceuticals Division sales outside of China and Japan grew 1-2% in developed markets such as Australia/New Zealand, Korea, and Taiwan.

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Bayer Pharmaceuticals strengthens pharma production network.

Key growth drivers also came from South Asia with India delivering a strong 11%3 growth and Pakistan at 2%3, and the ASEAN cluster achieving 9%3 average growth across Indonesia, Malaysia, Philippines, Singapore, Thailand, and Vietnam.

Newly appointed Head of Commercial Operations for Bayer’s Pharmaceuticals Division in Asia/Pacific, Ying Chen, said: “2021 has been a successful year for Bayer’s Pharmaceuticals Division as we increased our efforts to focus on what matters most – delivering both innovative and essential medicines to patients in Asia/Pacific, despite the challenges from the pandemic.”

“Our consistent strong growth in the region is a testament to our innovation-driven portfolio that delivers value to patients in areas of high unmet medical needs.”

Outside of China and Japan, sales of Xarelto® in Asia/Pacific grew significantly by 12%3 in 2021 over the previous year. Similarly, there was a 10%3 increase in Eylea® sales and it represents one of the most successful product launches in Asia/Pacific to date.

Xarelto remains the most broadly studied novel oral anticoagulant with 100 million patients treated in 130 countries since 2008. More than 47 million vials/pre-filled syringes of Eylea have been sold globally, generating 6.8 million patient-years of experience in 100 countries.

Bayer plans to grow its global pharmaceuticals sales by 3-4% in 20222 on a currency and portfolio adjusted basis. The market outlook for the Asia/Pacific region remains positive, as IQVIA projects an average growth rate of 4-5% in the pharmaceutical markets across the region from 2021 to 2025.

2022 will be a breakthrough year for Bayer’s Pharmaceuticals Division in Asia/Pacific with four upcoming launches of innovative products in the fields of cardiovascular disease and oncology.

Chronic and Cardiovascular Diseases Leading Causes of Death

Every year across the globe, 15 million people die before age 70 from chronic diseases which include cardiovascular diseases, cancers, diabetes, and obesity. Couple that with the fact that by 2050, one in four people in Asia/Pacific will be over 60 years old.

Along with ageing, the greatest cumulative impact on health comes from the striking rise in metabolic risks – namely high Body Mass Index (BMI), high blood sugar, high blood pressure, and high cholesterol – accounting for nearly 20% of total health loss worldwide in 2019.

Diabetes prevalence is increasing in Asia/Pacific, with over 70 million people living with diabetes in India alone. One in 10 adults worldwide is living with diabetes and out of those, almost half are undiagnosed.

Bayer’s Finerenone, a non-steroidal, selective mineralocorticoid receptor (MR) antagonist has demonstrated positive kidney and cardiovascular (CV) outcomes in patients with chronic kidney disease (CKD) associated with type 2 diabetes (T2D).

Up to 40% of people living with diabetes have CKD, which increases the risk of renal failure/dialysis and CV outcomes.

Heart failure is the number one cause of death affecting more than 60 million people worldwide; 50% do not survive 5 years, and 1 in 5 patients will die in 2 years. One person in Australia is hospitalized for heart failure every 8 minutes.

Patients in Asia/Pacific suffer from worse outcomes with late presentation of symptoms and huge gaps in treatment for the past decade to address this unmet risk. The key is to optimize treatment of worsening heart failure early and prevent the next hospitalization.

To this effect, the European Society of Cardiology HF Guidelines Task Force published new guidelines in 2021 mentioning worsening heart failure for the first time and emphasized the urgency of establishing foundational therapies faster.

Many traditional therapies work by inhibiting signaling pathways. Bayer’s Vericiguat is a therapy that works by stimulating soluble guanylate cyclase (sGC), which leads to improved myocardial and vascular function.

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